Relationship between hysterectomy and severity of female stress urinary incontinence

Authors

  • Zahra Motaghed M.D, Department of Urology, Faculty of Medicine, Baqiyatallah University of Medical Sciences, Tehran, Iran

Keywords:

http://www.ephysician.ir/index.php/browse-issues/2017/6/726-4678#:~:text= Urinary Incontinence, Hysterectomy, Urodynamics, Valsalva Maneuver

Abstract

Background: Stress Urinary Incontinence (SUI) is one of the most reported health dilemmas of women suffering from lower urinary tract symptoms. 

Aim: To determine the relation between hysterectomy and severity of female SUI using Valsalva Leak Point Pressure (VLPP). 

Methods: This case-control study was conducted at a public urology clinic in Tehran in 2015. The study population was all female with SUI complaints who visited the clinic during 2015. We compared Valsalva leak point pressure in two groups of female SUI patients with and without hysterectomy history. The inclusion criteria were: not taking any alpha-blocker or anti-cholinergic medicines two weeks prior to the urodynamic test as well as no history of pelvic surgery or cesarean delivery in their lifetime. All qualified patients were invited to participate in the study randomly, and among them, 120 qualified patients agreed to participate by filling out the informed consent form. Data was gathered through direct interview, and double checked by patients' medical records. All the study variables including age, BMI, delivery number, hysterectomy and UTI history were entered and analyzed by estimating ordered logistic regression and by using Stata14.1 software.

Results: The mean of VLPP was 70.17 cmH2O in the group with hysterectomy history, and 94.55 cmH2O in those without hysterectomy history. The difference of VLPP pressure between the two studied groups were significant (p<0.05), even after control of confounding variables. Also, the odds of severe SUI among hysterectomy group patients was 6.3 times more than no hysterectomy (OR=6.32, p<0.001).

Conclusions: Our study confirms significant relation between hysterectomy and SUI severity measured by Valsalva leak point pressure. Hysterectomy patients are more likely to suffer from more severe grades of SUI.

References

Haylen BT, de Ridder D, Freeman RM, Swift SE, Berghmans B, Lee J, et al. An International

Urogynecological Association (IUGA)/International Continence Society (ICS) joint report on the

terminology for female pelvic floor dysfunction. Neurourol Urodyn. 2010; 29(1): 4-20. doi:

1002/nau.20798. PMID: 19941278.

Sangsawang B. Risk factors for the development of stress urinary incontinence during pregnancy in

primigravidae: a review of the literature. Eur J Obstet Gynecol Reprod Biol. 2014; 178: 27-34. doi:

1016/j.ejogrb.2014.04.010. PMID: 24784708.

Altman D, Granath F, Cnattingius S, Falconer C. Hysterectomy and risk of stress-urinary-incontinence

surgery: nationwide cohort study. Lancet. 2007; 370(9597): 1494-9. doi: 10.1016/S0140-6736(07)61635-3.

Aoun F, Roumeguère T. Lower urinary tract dysfunction following radical hysterectomy. Prog Urol. 2015;

(17): 1184-90. doi: 10.1016/j.purol.2015.08.311. PMID: 26362076.

Zhang L, Zhu L, Xu T, Lang J, Li Z, Gong J, et al. A Population-based Survey of the Prevalence, Potential

Risk Factors, and Symptom-specific Bother of Lower Urinary Tract Symptoms in Adult Chinese Women.

Eur Urol. 2015; 68(1): 98-112. doi: 10.1016/j.eururo.2014.12.012. PMID: 25572826.

Stothers L, Friedman B. Risk factors for the development of stress urinary incontinence in women. Curr

Urol Rep. 2011; 12(5): 363-9. doi: 10.1007/s11934-011-0215-z. PMID: 21938471.

Aoun F, Peltier A, Van Velthoven R. Lower urinary tract dysfunction in pelvic gynecologic cancer: The

role of urodynamics. Adv Urol. 2014; 2014: 303958. doi: 10.1155/2014/303958. PMID: 25506360,

PMCID: PMC4259142.

Plotti F, Angioli R, Zullo MA, Sansone M, Altavilla T, Antonelli E, et al. Update on urodynamic bladder

dysfunctions after radical hysterectomy for cervical cancer. Crit Rev Oncol Hematol. 2011; 80(2): 323-9.

doi: 10.1016/j.critrevonc.2010.12.004. PMID: 21277788.

Gustafsson C, Ekström Å, Brismar S, Altman D. Urinary incontinence after hysterectomy—three-year

observational study. Urology. 2006; 68(4): 769-74. doi: 10.1016/j.urology.2006.04.001. PMID: 17070350.

de Tayrac R, Chevalier N, Chauveaud-Lambling A, Gervaise A, Fernandez H. Is vaginal hysterectomy a

risk factor for urinary incontinence at long-term follow-up? Eur J Obstet Gynecol Reprod Biol. 2007;

(2): 258-61. doi: 10.1016/j.ejogrb.2006.01.032. PMID: 16876308.

EL-Hefnawy AS, Wadie BS. Severe stress urinary incontinence: Objective analysis of risk factors.

Maturitas. 2011; 68(4): 374-7. doi: 10.1016/j.maturitas.2011.01.005. PMID: 21292413.

Kuo HC. Videourodynamic analysis of the relationship of Valsalva and cough leak point pressures in

women with stress urinary incontinence. Urology. 2003; 61(3): 544-8. doi: 10.1016/S0090-4295(02)02500- 1. PMID: 12639643.

Brown JS, Sawaya G, Thom DH, Grady D. Hysterectomy and urinary incontinence: a systematic review.

Lancet. 2000; 356(9229): 535-9. doi: 10.1016/S0140-6736(00)02577-0. PMID: 10950229.

Allahdin S, Harrild K, Warraich QA, Bain C. Comparison of the long‐term effects of simple total

abdominal hysterectomy with transcervical endometrial resection on urinary incontinence. BJOG. 2008;

(2): 199-204. doi: 10.1111/j.1471-0528.2007.01546.x. PMID: 17970792.

Miller JJ, Botros SM, Beaumont JL, Aschkenazi SO, Gamble T, Sand PK, et al. Impact of hysterectomy on

stress urinary incontinence: an identical twin study. Am J Obstet Gynecol. 2008; 198(5): 565.e1-4. doi:

1016/j.ajog.2008.01.046. PMID: 18455535.

Published

2022-01-18

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