Do estrogen antagonists and anti-androgens prevent the COVID-19’s pulmonary involvement?

Authors

  • Mehrdad Jalalian Editor-in-Chief, Electronic Physician Journal, Mashhad, Iran.

Keywords:

COVID-19, Prophylaxis, Coronavirus, ACE2, S-protein, Estrogen, Testosterone

Abstract

Male and female hormones are upregolators of expression of Angiotensin-converting Enzyme 2 (ACE2) gene. This short article proposes a hypothesis about the potential effect of estrogen antagonists and anti-androgens in preventing pulmonary involvement in COVID-19 infection through their downregulatory effect on ACE2 expression.

References

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Published

2021-12-11