Simulation of therapeutic electron beam tracking through a non-uniform magnetic field using finite element method

Authors

  • Reza Maskani Ph.D. Candidate of Medical Physics, Student Research Committee, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

Keywords:

Linear accelerator; Electron beam; Magnetic field; NdFeb, Particle tracking simulation

Abstract

Introduction: In radiotherapy, megaelectron volt (MeV) electrons are employed for treatment of superficial cancers. Magnetic fields can be used for deflection and deformation of the electron flow. A magnetic field is composed of non-uniform permanent magnets. The primary electrons are not mono-energetic and completely parallel. Calculation of electron beam deflection requires using complex mathematical methods. In this study, a device was made to apply a magnetic field to an electron beam and the path of electrons was simulated in the magnetic field using finite element method. 

Methods: A mini-applicator equipped with two neodymium permanent magnets was designed that enables tuning the distance between magnets. This device was placed in a standard applicator of Varian 2100 CD linear accelerator. The mini-applicator was simulated in CST Studio finite element software. Deflection angle and displacement of the electron beam was calculated after passing through the magnetic field. By determining a 2 to 5cm distance between two poles, various intensities of transverse magnetic field was created. The accelerator head was turned so that the deflected electrons became vertical to the water surface. To measure the displacement of the electron beam, EBT2 GafChromic films were employed. After being exposed, the films were scanned using HP G3010 reflection scanner and their optical density was extracted using programming in MATLAB environment. Displacement of the electron beam was compared with results of simulation after applying the magnetic field. 

Results: Simulation results of the magnetic field showed good agreement with measured values. Maximum deflection angle for a 12 MeV beam was 32.9° and minimum deflection for 15 MeV was 12.1°. Measurement with the film showed precision of simulation in predicting the amount of displacement in the electron beam.

Conclusion: A magnetic mini-applicator was made and simulated using finite element method. Deflection angle and displacement of electron beam were calculated. With the method used in this study, a good prediction of the path of high-energy electrons was made before they entered the body.

 

References

Hogstrom KR, Almond PR. Review of electron beam therapy physics. Phys Med Biol. 2006; 51(13): R455- 89. doi: 10.1088/0031-9155/51/13/R25. PMID: 16790918.

Bostick WH. Possible Techniques in Direct-Electron-Beam Tumor Therapy. Phys Rev. 1950; 77(4): 564-5.

doi: 10.1103/PhysRev.77.564.

Whitmire DP, Bernard DL, Peterson MD, Purdy JA. Magnetic enhancement of electron dose distribution in

a phantom. Med Phys. 1977; 4(2): 127-31. doi: 10.1118/1.594309. PMID: 850509.

Becchetti FD. High energy electron beams shaped with applied magnetic fields could provide a competitive

and cost-effective alternative to proton and heavy-ion radiotherapy. For the proposition. Med Phys. 2002;

(10): 2435-6. doi: 10.1118/1.1510453. PMID: 12408319.

Papiez L. Very high energy electromagnetically-scanned electron beams are an attractive alternative to

photon IMRT. For the proposition. Med Phys. 2004; 31(7): 1946-8. doi: 10.1118/1.1760769. PMID:

Earl MA, Ma L. Depth dose enhancement of electron beams subject to external uniform longitudinal

magnetic fields: a Monte Carlo study. Med Phys. 2002; 29(4): 484-91. doi: 10.1118/1.1461374. PMID:

Bielajew AF. The effect of strong longitudinal magnetic fields on dose deposition from electron and photon

beams. Med Phys. 1993; 20(4): 1171-9. doi: 10.1118/1.597149. PMID: 8413027.

Nardi E, Barnea G, Ma CM. Electron beam therapy with coil-generated magnetic fields. Med Phys. 2004;

(6): 1494-503. doi: 10.1118/1.1711477. PMID: 15259653.

Wessels BW, Paliwal BR, Parrott MJ, Choi MC. Characterization of Clinac‐18 electron‐beam energy

using a magnetic analysis method. Med Phys. 1979; 6(1): 45-8. doi: 10.1118/1.594550. PMID: 440231.

Belousov AV, Varzar SM, Chernyaev AP. Simulation of the conditions of photon and electron beam

irradiation in magnetic fields for increasing conformity of radiation therapy. Bull Russ Acad Sci Phys.

; 71(6): 841-3. doi: 10.3103/S1062873807060172.

Brown D, Ma BM, Chen Z. Developments in the processing and properties of NdFeB-type permanent

magnets. J Magn Magn Mater. 2002; 248(3): 432-40. doi: 10.1016/S0304-8853(02)00334-7.

CST STUDIO SUITE. Available from: https://www.cst.com/Products/CSTS2.

Inc. MSM. Design Guide. Available from: http://www.magnetsales.com/design/designg.htm.

Maskani R, Tahmasebibirgani MJ, Hoseini-Ghahfarokhi M, Fatahiasl J. Determination of Initial Beam

Parameters of Varian 2100 CD Linac for Various Therapeutic Electrons Using PRIMO. Asian Pac J Cancer

Prev. 2014; 16(17): 7795-801. doi: 10.7314/APJCP.2015.16.17.7795. PMID: 26625800.

Arjomandy B, Tailor R, Zhao L, Devic S. EBT2 film as a depth-dose measurement tool for radiotherapy

beams over a wide range of energies and modalities. Med phys. 2012; 39(2): 912-21. doi:

1118/1.3678989. PMID: 22320801.

Damrongkijudom N, Oborn B, Butson M, Rosenfeld A. Measurement of magnetic fields produced by a

“Magnetic deflector” for the removal of electron contamination in radiotherapy. Australas Phys Eng Sci

Med. 2006; 29(4): 321-7. doi: 10.1007/BF03178398. PMID: 17260587.

Tahmasebi-Birgani MJ, Bayatiani MR, Seif F, Zabihzadeh M, Shahbazian H. Electron Beam Dose

Distribution in the Presence of Non-Uniform Magnetic Field. Iran J Med Phys. 2014; 11(1): 195-204. doi:

22038/ijmp.2014.2630.

Damrongkijudom N, Oborn B, Butson M, Rosenfeld A. Measurement and production of electron deflection

using a sweeping magnetic device in radiotherapy. Australas Phys Eng Sci Med. 2006; 29(3): 260-6. doi:

1007/BF03178575. PMID: 17058588.

Keyvanloo A, Burke B, Warkentin B, Tadic T, Rathee S, Kirkby C, et al. Skin dose in longitudinal and

transverse linac-MRIs using Monte Carlo and realistic 3D MRI field models. Med phys. 2012; 39(10):

-21. doi: 10.1118/1.4754657. PMID: 23039685.

Kirkby C, Stanescu T, Rathee S, Carlone M, Murray B, Fallone BG. Patient dosimetry for hybrid MRIradiotherapy systems. Med Phys. 2008; 35(3): 1019-27. doi: 10.1118/1.2839104. PMID: 18404937.

Published

2022-01-18

Issue

Section

Articles