Effect of self-acupressure on fasting blood sugar (FBS) and insulin level in type 2 diabetes patients: a randomized clinical trial
A randomized clinical trial
Keywords:
Acupressure, Complementary therapies, Type 2 DiabetesAbstract
Background: Uncontrolled symptoms of diabetes can lead to irreparable damage to vital organs. Despite the global trend towards the use of complementary alternative therapies, few studies have evaluated the effectiveness of self-acupressure in diabetes patients. Objective: The aim of this study was to determine the effect of self-acupressure on FBS and insulin level in type 2 diabetes patients. Methods: This randomized clinical trial was performed from September 2016 to February 2017. A total of 60 diabetic patients were selected from diabetes clinic in Rafsanjan in Iran, according to inclusion and exclusion criteria and then assigned to 2 groups (30 in acupressure and 30 in control) randomly by the minimization method. The intervention group received acupressure at ST-36, LIV-3, KD-3 and SP-6 points bilaterally for five minutes for each point in 10 seconds pressure and 2 seconds rest periods. Subjects in the control group received no intervention. The FBS and insulin levels were measured before and after the intervention for both groups. The data were analyzed by SPSS version 16 by the Chi-square test, independent-samples t-test, and paired-samples t-test. A level of 0.05 was considered significant for examining the hypotheses. Results: There were no significant differences between the acupressure and control group regarding age, sex and level of education. The insulin level significantly increased after treatment in the acupressure group (p=0.001). There were no significant differences between the levels of insulin in study or control groups. Serum FBS level decreased significantly after intervention in the acupressure group compared to the control group (p=0.02). Conclusion: Self-acupressure as a complementary alternative medicine can be a helpful complementary method in reducing FBS and increasing insulin levels in type 2 diabetic patients. Trial registration: This trial was registered at the Iranian Registry of Clinical Trials with clinical trial registration number: IRCT2016122131459N1. Funding: This study was financially sported by Deputy of Research and Technology of Rafsanjan University of Medical Sciences (Ref: 20.519).References
Ogurtsova K, da Rocha Fernandes J, Huang Y, Linnenkamp U, Guariguata L, Cho N, et al. IDF Diabetes
Atlas: Global estimates for the prevalence of diabetes for 2015 and 2040. Diabet Res Clin Pract. 2017; 128:
-50. doi: 10.1016/j.diabres.2017.03.024.
Whiting DR, Guariguata L, Weil C, Shaw J. IDF diabetes atlas: Global estimates of the prevalence of
diabetes for 2011 and 2030. Diabet res clin pract. 2011; 94(3): 311-21. doi: 10.1016/j.diabres.2011.10.029.
American Diabetes Association. Diagnosis and classification of diabetes mellitus. Diabetes care. 2014;
(S1): S81-90. doi: 10.2337/dc 14-S018. PMID: 24357215.
Tomas-Carus P, Ortega-Alonso A, Pietilainen KH, Santos V, Goncalves H, Ramos J, et al. A randomized
controlled trial on the effects of combined aerobic-resistance exercise on muscle strength and fatigue,
glycemic control and health-related quality of life of type 2 diabetes patients. J Sport Med Phys Fitness. 2016; 56(5): 572-8. PMID: 27285345.
Qian F, Korat AA, Malik V, Hu FB. Metabolic effects of monounsaturated fatty acid–enriched diets
compared with carbohydrate or polyunsaturated fatty acid–enriched diets in patients with type 2 diabetes: A
systematic review and meta-analysis of randomized controlled trials. Diabetes Care. 2016; 39(8): 1448-57.
doi: 10.2337/dc16-0513. PMID: 27457635, PMCID: PMC4955926.
Maruthur NM, Tseng E, Hutfless S, Wilson LM, Suarez-Cuervo C, Berger Z, et al. Diabetes Medications as
Monotherapy or Metformin-Based Combination Therapy for Type 2 Diabetes: A Systematic Review and
Meta-analysis. Ann Intern Med. 2016; 164(11): 740-51. doi: 10.7326/M15-2650. PMID: 27088241.
Pickup JC, Reznik Y, Sutton AJ. Glycemic Control During Continuous Subcutaneous Insulin Infusion
Versus Multiple Daily Insulin Injections in Type 2 Diabetes: Individual Patient Data Meta-analysis and
Meta-regression of Randomized Controlled Trials. Diabetes Care. 2017; 40(5): 715-22. doi: 10.2337/dc16- 2201. PMID: 28428322.
Peregoy JA, Clarke TC, Jones LI, Stussman BJ, Nahin RL. Regional variation in use of complementary
health approaches by US adults. NCHS data brief. 2014; (146): 1-8. PMID: 24750666, PMCID:
PMC4562209.
Fogarty S, Smith CA, Hay P. The role of complementary and alternative medicine in the treatment of
eating disorders: A systematic review. Eat behave. 2016; 21: 179-88. doi: 10.1016/j.eatbeh.2016.03.002.
PMID: 26970732.
Rousdy A. Effectiveness of Acupressure at the Zusanli (ST-36) Acupoint as a Comfortable Treatment for
Diabetes Mellitus: A Pilot Study in Indonesia. J Acupunct Meridian Stud. 2017; 10(2): 96-103. doi:
1016/j.jams.2016.12.003. PMID: 28483191.
Sierpina VS, Frenkel MA. Acupuncture: A clinical review. South Med J. 2005; 98(3): 330-7. doi:
1097/01.SMJ.0000140834.30654.0F
Song HJ, Seo HJ, Lee H, Son H, Choi SM, Lee S. Effect of self-acupressure for symptom management: A
systematic review. Complementary therapies in medicine. 2015; 23(1): 68-78. doi:
1016/j.ctim.2014.11.002.
Khalaf AJ, Whitford DL. The use of complementary and alternative medicine by patients with diabetes
mellitus in Bahrain: A cross-sectional study. BMC complementary and alternative medicine. 2010; 10(1):
doi: 10.1186/1472-6882-10-35.
Bay R, Bay F. Combined Therapy Using Acupressure Therapy, Hypnotherapy, and Transcendental
Meditation versus Placebo in Type 2 Diabetes. J Acupunct Meridian Stud. 2011; 4(3): 183-6. doi:
1016/j.jams.2011.09.006. PMID: 21981869.
Medagama AB, Bandara R. The use of Complementary and Alternative Medicines (CAMs) in the
treatment of diabetes mellitus: Is continued use safe and effective? Nutr J. 2014; 13(1): 102. doi:
1186/1475-2891-13-102. PMID: 25331834, PMCID: PMC4210501.
Covington MB. Traditional Chinese medicine in the treatment of diabetes. Diabetes spectrum. 2001; 14(3):
-9. doi: 10.2337/diaspect.14.3.154.
Dey L, Attele A. Type 2 diabetes. Tradit Chinese Med. 2011; 231(1): 1-16.
Torkzahrani S, Mahmoudikohani F, Saatchi K, Sefidkar R, Banaei M. The effect of acupressure on the
initiation of labor: A randomized controlled trial. Women and Birth. 2017; 30(1): 46-50. doi:
1016/j.wombi.2016.07.002. PMID: 27444642.
Bazarganipour F, Taghavi SA, Allan H, Beheshti F, Khalili A, Miri F, et al. The effect of applying pressure
to the LIV3 and LI4 on the symptoms of premenstrual syndrome: A randomized clinical trial. Complement
Ther Med. 2017; 31: 65-70. doi: 10.1016/j.ctim.2017.02.003. PMID: 28434473.
Güçel F, Bahar B, Demirtas C, Mit S, Çevik C. Influence of acupuncture on leptin, ghrelin, insulin and
cholecystokinin in obese women: A randomised, sham-controlled preliminary trial. Acupunct Med. 2012;
(3): 203-7. doi: 10.1136/acupmed-2012-010127. PMID: 22729015.
Kumar M. Treatment of Diabet Trough Acupuncture. IRJC. 2013; 2(2): 175-88.
Cabıoğlu MT, Ergene N. Changes in levels of serum insulin, C-peptide and glucose after
electroacupuncture and diet therapy in obese women. The American journal of Chinese medicine. 2006;
(03): 367-76. doi: 10.1142/S0192415X06003904
Peplow PV, Baxter GD. Electroacupuncture for Control of Blood Glucose in Diabetes: Literature Review. J
Acupunct Meridian Stud. 2012; 5(1): 1-10. doi: 10.1016/j.jams.2011.11.018. PMID: 22309901.
Szczudlik A, Lypka A. Acupuncture-induced changes in human plasma insulin level. Acupunct Electrother
Res. 1984; 9(1): 1-9. PMID: 6145307.
Liu C, Yu L, Lin C, Lin S. Effect of auricular pellet acupressure on antioxidative systems in high-risk
diabetes mellitus. J Altern Complement Med. 2008; 14(3): 303-7. doi: 10.1089/acm.2006.6064. PMID:
Jin KK, Chen L, Pan JY, Li JM, Wang Y, Wang FY. Acupressure therapy inhibits the development of
diabetic complications in Chinese patients with type 2 diabetes. J Altern Complement Med. 2009; 15(9):
-32. doi: 10.1089/acm.2008.0608. PMID: 19757980.
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