The Axis “Human Papillomavirus - Anal Squamous Cell Carcinoma”: A Review

Authors

  • Ana Carolina Borges Monteiro State University of Campinas (UNICAMP), Brazil
  • Reinaldo Padilha França State University of Campinas (UNICAMP), Brazil
  • Yuzo Iano State University of Campinas (UNICAMP), Brazil
  • Valeria Tananska Medical University of Plovdiv, Plovdiv, Bulgaria
  • Abdeldjalil Khelassi Abou Bakr Belkaid University of Tlemcen, Algeria
  • Rangel Arthur Faculty of Technology (FT), UNICAMP, Brazil

DOI:

https://doi.org/10.26415/2572-004X-vol3iss4p471-484

Abstract

Background: Anal Squamous Cell Carcinoma (ASCC) is an infrequent neoplasia that represents 2% of the digestive tumors and it has a growing incidence.

Objective: This investigation (i) studies the pathogenesis of an increasingly prevalent disease, (ii) its treatment and prognosis along with (iii) a bibliographical review of the main characteristics of the Human Papillomavirus (HPV) as well as its effects on humans.

Methods: A literature review is performed, comprising articles up to 2019 and cross-research manuscripts with the initial research.

Results: Several studies demonstrate the HPV role as a significant risk factor to the development of ASCC, as well as its higher incidence in HIV-positive individuals and in those who engage in receptive anal intercourse. Future trends in theragnostic using information technology are examined.

Conclusions: ASCC is a neoplasm mostly associated with HPV. Many studies are needed to improve the treatment as well as in the evaluation of the tumor characteristics.

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Published

2020-02-01

Issue

Vol. 3 No. 4 (2019): October-December 2019

Section

Medical technologies

How to Cite

“The Axis ‘Human Papillomavirus - Anal Squamous Cell Carcinoma’: A Review”. Medical Technologies Journal, vol. 3, no. 4, Feb. 2020, pp. 471-84, https://doi.org/10.26415/2572-004X-vol3iss4p471-484.

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